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Tumor-induced osteomalacia

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Tumor-induced osteomalica
Pathology
Type

Paraneoplastic syndrome

Cause(s)

Usually a benign mesenchymal tumor

Symptoms

Increasing muscle pain, bone pain, fatigue, bone fractures

Mortality Rate

Low

Treatments

Removal of tumor with surgery

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  [Source]


Tumor-induced osteomalica is a rare paraneoplastic syndrome resulting from the increased excretion of phosphate salts in the urine. They are usually caused by benign mesenchymal tumors, such as a sarcoma.

As the phosphate salt level drops, the patient starts to suffer from muscle pain, bone pain and fatigue, often leading to weakened bones and fractures.

The condition can usually be stopped by removing the tumor causing the condition. However, the tumor can often be very difficult to locate.

Tumor-induced osteomalacia at Wikipedia

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