Ad blocker interference detected!
Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers
Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.
Tissue Plasminogen Activator is a component of blood that plays a role in the break-up of clots. In its pharmaceutical preparation, it is used to break up existing clots that will not respond to heparin or warfarin. It is one of the first drugs used when a patient is suffering from a stroke caused by lack of blood flow. It can also be used to treat embolism and heart attack. However, it's usefulness decreases as time passes since the onset of symptoms and, after about 3–4 hours, it is contraindicated for these conditions.
Although TPA can be isolated from the rest of blood, it is usually produced with recombinant DNA technology.