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|Birthplace||New York City, NY|
|Episode||You Must Remember This|
Holmes originally studied comparative literature in both the United States and France. While working as a research assistant, she was asked to do research for a documentary. From there, she worked on other documentaries and eventually turned to acting in 1998 in the film Edge of Seventeen. She has also had featured roles in Taken, NYPD Blue, Six Feet Under, Invasion, Vanished and Persons Unknown.