House Wiki


6,714pages on
this wiki
Add New Page
Talk0 Share

Perinuclear Anti-Neutrophil Cytoplasmic Antibodies or p-ANCA, are a type of antibody in the immune system that attaches to the negatively charged DNA in the nucleus of a cell. When stained with a fluorescent stain, the antibodies indicate the location of the nucleus as they surround it.

Although a key part of the immune system, they can be a component of several autoimmune diseases including ulcerative colitis, Churg-Strauss syndrome, primary sclerosing cholangitis, polyarteritis nodosa, microscopic polyangitis, glomerulonephritis, rheumatoid arthritis and vasculitis. However, although the presence of p-ANCA in higher than normal quantities can help confirm a diagnosis of these conditions, the absence of high levels does not rule them out.

P-ANCA at Wikipedia

Ad blocker interference detected!

Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers

Wikia is not accessible if you’ve made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected.

Also on Fandom

Random Wiki