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Fault in any of a number of genes


Uncontrolled growth of tumors

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Neurofibromatosis is any of a number of distinct genetic conditions that result in a high probability of tumor formation. However, all the conditions are caused by inheriting the single defective gene from a parent with the condition. However, in any given patient, the disease can be of varying severity due to the expression of other related genes. They fall into three categories:

  • Type I – the tumors are generally benign, but can compress nerves and other tissues
  • Type II – where the tumors form around the acoustic nerves, leading to hearing loss
  • Schwannomatosis – where painful schwannomas grow around several different types of nerves

Neurofibromatosis at Wikipedia

Neurofibromatosis type II at Wikipedia

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