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Microscopic polyangiitis

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Microscopic polyangiitis
Pathology
Type

Autoimmune

Cause(s)

Overproduction of p-ANCA

Symptoms

Fever, anorexia, weight loss, fatigue, kidney failure

Mortality Rate

Moderate

Treatments

Steroids, cyclophosphamide and plasmapheresis

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Microscopic polyangitis is an autoimmune disease that affects the small blood vessels of the body. Although its triggers are poorly understood, it is linked to the production of an antibody, p-ANCA, that affects those particular blood vessels. It can present with a prosaic constellation of symptoms including fever, loss of appetite, weight loss, fatigue and, in serious cases, kidney failure.

Like most autoimmune diseases, there is no cure for the condition, but a course of high dose prednisone or cyclophosphamide can alleviate the symptoms and slow the progression of the disease.

Microscopic polyangiitis at Wikipedia

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