Hodgkin's lymphoma





Itch, night sweat, weight loss, enlargement of lymph nodes, enlargement of spleen, enlargement of liver, pain in affected lymph nodes following consumption of alcohol, back pain, cyclical fever

Mortality Rate

About 10% over 10 years


Radiation therapy, chemotherapy

Show Information

Hodgkin lymphoma (1) mixed cellulary type

A biopsy slide showing Hodgkin's lymphoma, courtesy Wikipedia Commons

Hodgkin's lymphoma or Hodgkin's disease is a form of lymphoma characterized by a progressive spread of the symptoms from one lymph node to another. It was first described by Thomas Hodgkin in 1832. For some reason, it is most common in patients between 15 and 35 and in patients over 55, but is far less common in patients between 35 and 55. Its causes are unknown and it is believed it occurs due to a number or factors (which may be different from patient to patient) such as age, low hemoglobin, sex (more likely in males), low serum albumin, infection with Epstein-Barr virus or HIV and use of human growth hormone.

Unlike many other lymphomas, Hodgkin's does not spread randomly, but appears to start in one lymph node and then spreads to the next in line. As such, it progresses slowly. Patient's are classified depending on how many lymph nodes are involved at the time of diagnosis.

Treatment is with radiation therapy or chemotherapy depending on the patient and the spread of the disease. Experimental treatments involving stem cells are also available.

Hodgkin's lymphoma at NIH

Hodgkin's lymphoma at Wikipedia

Hodgkin's lymphoma at Mayo Clinic

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