Haff disease



unidentified toxin

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Haff disease is a syndrome of unexplained rhabdomyolysis caused by an unidentified toxin following consumption of certain types of fish. It was first described in 1924 in the vicinity of Königsberg, Germany (now Kaliningrad, Russia), in people staying around the haff (German: lagoon). The first cases in the US were reported in California and Missouri in 1997, all after the consumption of buffalo fish

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