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- Emily (mother) - The mother of Adam, the burn patient in Distractions, portrayed by Lisa Darr
- Emily (daughter) - The daughter of Tucker, the patient in Wilson (episode), portrayed by Jessica Whitaker
- Emily (prostitute) - House's favorite hurdy-gurdy playing hooker in Out of the Chute, After Hours and We Need the Eggs, portrayed by Noelle Bellinghausen
- Emily Koppelman - The wife of Bill Koppelman in Nobody's Fault, portrayed by Audrey Marie Anderson
- Emily Lawson - The patient in The C Word, portrayed by Rachel Eggleston