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DeSantos has had featured roles in Literally Dysfunctional, Ray Donovan, General Hospital and The Red Road.
- Appeared with Ivana Milicevic on Banshee
- Appeared with Vinessa Shaw on Ray Donovan
- Appeared with Thomas Dekker on Enter the Dangerous Mind
- Appeared with Sasha Pieterse on Pretty Little Liars
- Appeared with Steve Valentine on Crossing Jordan