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Carcinoid syndrome

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Carcinoid syndrome
Pathology
Type

Paraneoplastic syndrome

Cause(s)

Carcinoid tumors

Symptoms

Flushing, diarrhea

Mortality Rate

10-20% over five years

Treatments

Address symptoms, surgical removal of tumors

Show Information
  [Source]

Carcinoid syndrome is a paraneoplastic syndrome associated with carcinoid tumors.  It's primary symptoms are flushing and diarrhea, but it can lead to heart failure and bronchoconstriction.  It occurs in about 5% of carcinoid patients.

Carcinoid tumors can produce serotonin and kallikrein, which lead to the syndrome.  

Treatment usually focusses on the symptoms, using drugs that counteract the effect of the hormones involved.  Carcinoid tumors are usually very hard to locate, often ruling out surgery.  The side effects of the other available treatment, chemotherapy, is often worse than the syndrome's symptoms.

Carcinoid syndrome at Wikipedia

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