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The web site Buddy TV picked it's 20 favourite House, M.D. patients in May, 2012, just after the end of the series.
- Cannibal Danny Jennings from Fall From Grace, portrayed by Chris Marquette
- Amber Volakis from Wilson's Heart, played by Anne Dudek
- Drug seeker Mid 30s man, standing in for Gregory House, played by Carmen Electra, James Saxenmeyer and Hugh Laurie
- Teenage jerk Nate from The Jerk, portrayed by Nick Lane
- Savant Patrick Obyedkov from Half-Wit, portrayed by Dave Matthews
- Nun Sister Mary Augustine from Damned If You Do, played by Elizabeth Mitchell
- Fun seeking Fran from Airborne, played by Jenny O'Hara
- Faith healer Boyd from House vs. God, played by Thomas Dekker
- Hostage taker Jason from Last Resort, played by Zeljko Ivanek
- Performance artist Afsoun Hamidi from Moving On, played by Shohreh Aghdashloo
- Philanthropist Benjamin Byrd from Charity Case, played by Wentworth Miller
- Uptight Dr. Peter Treiber from Post Mortem, played by Jamie Elman
- Locked-in Lee from Locked In, played by Mos Def
- One-night-stand Spencer from Lucky Thirteen, played by Angela Gots
- Dictator President Dibala from The Tyrant, played by James Earl Jones
- Soap star Evan Greer from Living the Dream, played by Jason Lewis
- Author Alice Tanner from Unwritten, played by Amy Irving
- Death row inmate Clarence from Acceptance, played by LL Cool J
- Morbidly obese George from Que Será Será, played by Pruitt Taylor Vince
- Drug seeker Oliver from Everybody Dies, played by James LeGros