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Anti-fungals are a class of pharmaceuticals used in the treatment of fungal infections. They fall into four broad groups:

  • The polyenes, such as Amphotericin B, which work by increasing the leakage of certain vital chemicals like potassium and sodium from fungal cells but not animals cells.
  • The azoles like itraconazole, which inhibit an enzyme critical to fungal cell membranes
  • The allylamines, which inhibit a different but similarly important enzyme
  • The echinocadines, which inhibit the growth of fungal cell walls and are particularly useful in immunocompromised patients

Anti-fungals, unlike antibiotics, have severe side effects and must be used judiciously. Among the most common effects are liver toxicity, allergic reactions and drug interactions.

Antifungal medication at Wikipedia

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